1.Introduction 2.Historical Prospective: Antimicrobials and their Resistances 3.Classification Systems of Antimicrobials 4.Principles and Mechanisms of Action of Antibiotics 5.Antibiotics: Indications and Contraindications in Veterinary Therapeutics 6.Mechanism of Bacterial Resistance towards Antibiotics  7.Factors Affecting Antimicrobial Resistance Phenomenon 8.Sample Collection and Transportation Methodologies 9.Methods of Antimicrobial Susceptibility Testing 10.Methodologies for Phenotypic Detection of Specific Resistance Mechanisms 11.Factors Affecting Antimicrobial Susceptibility Testing 12.Guidelines for Successful Antimicrobial Therapy for Diseased Animals 13.Antimicrobial Resistances: Genes and Associated Mechanisms 14.Strategies for Prevention and Control of Antimicrobial Resistance in Animals